For the price of a cup of coffee a day you can join a select group of visionaries who are standing shoulder to shoulder as the first vanguard in the real war on aging. Read More...
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Latest Members
Jens Wiechers The Royal-Gordon Family Anonymous joseph yaskus David Bridgham Willie Jerome Mitchell ParaCPA, LLC Richard H. Shinn Forever21 C Carlino Robert Raiford Nenad Ilincic Julian G. Franco G. Hynes Jason Grogan Robert T Shinn
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What The Experts Say
 "It's not just better medical care, it's advances [in research] that will allow us to really slow down aging ... People have wanted it forever, and now here it is. Now that we have all these research tools, we can work on it seriously." ref
Steve Austad Ph.D.
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| The Methuselah Mouse Prize is the premiere effort of The Methuselah Foundation™; a scientific competition designed to draw attention to the ability of new technologies to slow and even reverse the damage of the aging process, preserving health and wisdom in a world that sorely needs it. Read More... |
IMPORTANT: Register for SENS 3 Today! |
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New! Check the Methuselah Foundation Blog for updates on our activities and let us know how we're doing!
Opportunity! Contributions to SENS research will be matched by 50% from Peter Thiel. Donate Now!
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| Former Prize Winner Andrzej Bartke, PhD., Re-enters the Mprize Competition |
 Lorton, VA - The Methuselah Foundation is pleased to announce that
Professor Andrzej Bartke has again taken up the challenge to compete in
the Mprize competition. Professor Bartke is Professor of Physiology and
Internal Medicine, Director of Geriatric Medicine and Distinguished
Scholar at Southern Illinois School of Medicine. The Mprize ®
, a scientific research prize aimed at encouraging scientists to find a
way to reverse the aging process, is a primary activity of the
Methuselah Foundation. The Mprize fund continues to grow and currently
stands at close to $4.5 Million. Prizes will be awarded to research
groups that can most successfully extend the life span of laboratory
mice. |
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2007-09-04 00:00:00
Admin
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| Internet Entrepreneur Brian Cartmell Donates $100,000 to the Methuselah Foundation |
| Lorton,
VA - The Methuselah Foundation is pleased to announce a generous $100,000
donation from serial internet entrepreneur Brian Cartmell. Mr. Cartmell founded
eNIC, a domain registry company which grew to over half a million subscribers.
The success of eNIC under Cartmell's leadership led to its $35 Million
acquisition in 2001 by Verisign. He then founded Spam Arrest, developing and
patenting a novel challenge/response process for stopping unwanted email. |
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2007-08-20 00:00:00
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| Living Forever: Is It Possible? What Will Get Us There? |
by Arnold Kling
TCS Daily Aubrey de Grey is so deep into geek biogerontology that using "almost everyone thinks of" in the sentence quoted above does not strike him as rather generous. In reality, most of us are thinking "amyloid...amyloid...you're talking about the singer, right? No, no...what am I saying...Wasn't she the actress in that movie...?"Four years ago, I reported that de Grey foresees a not-too-distant future in which humans can reverse the effects of aging, raising the possibility of living healthy lives for hundreds of years. He has not backed away from that position, and this book, written by de Grey and his research associate Michael Rae, represents an update from his perspective. |
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2007-09-19 00:00:00
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| Who would not seize the chance to live to be 150? |
By James Wilsdon
Published: February 8 2006
With his scruffy jeans, piercing blue eyes and long red beard, Aubrey de Grey looks every inch the eccentric scientist. But in the past year, this self-taught biogerontologist, based in Cambridge university's genetics department, has attracted serious attention for his theories about ageing. |
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2006-02-08 20:35:39
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| Aubrey de Grey and the Mprize featured on 60 Minutes. |
On CBS New Year’s Day (Sunday 1/1/06, 7pm Eastern/Pacific, 6pm Central/Mountain) Morley Safer interviewed Dr. de Grey about his plans for extending human lifespan. In a special New Year’s edition of 60 Minutes, America’s number one rated news show talked to Dr. de Grey and other luminaries of the science of life extension who described how it might be possible for today’s baby boomers to enjoy radically longer healthy lives, and eventually roll back the clock to regain youthfulness. Also featured was Burt Rutan, builder of X-prize winning SpaceShip 1, and his plans for affordable space travel.
Click here for more. |
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2006-02-03 19:46:06
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| Wanted: 3D Virtual Reality Developer |
| Need committed and experienced C/C++ Visual Studio 2005 volunteer developer to do the following task:
• Create a simple 3D model of a boardroom (with 6 chairs, a table, and a whiteboard) using a light-weight 3D toolkit
• Create avatars (sitting in the chairs) with fully articulatable virtual necks. Able to direct the head direction via a mouse.
• The avatar's face is a video texture (supplied to you via a shared memory buffer).
• The boardroom whiteboard is a video texture (supplied for you via shared memory buffer)
• The avatar supports spatial audio, in that if an avatar on your left speaks, the sound appears to come from your left.
The overall executable must be small and does not have any external dependencies.
Volunteer must have extensive experience with 3D toolkits and have done something like this before. The task does not require any videoconferencing experience, the videoconferencing module is supplied for you. The volunteer must interface his/her system with the supplied videoconferencing software via a shared memory buffer interface.
Need committed and experienced C/C++ Visual Studio 2005 volunteer developer
to do the following task:
- Create a simple 3D model of a
boardroom (with 6 chairs, a table, and a whiteboard) using a light-weight
3D toolkit
- Create avatars (sitting in
the chairs) with fully articulatable virtual necks. Able to direct
the head direction via a mouse.
- The avatar's face is a video
texture (supplied to you via a shared memory buffer).
- The boardroom whiteboard is a
video texture (supplied for you via shared memory buffer)
- The avatar supports spatial
audio, in that if an avatar on your left speaks, the sound appears to come
from your left.
The overall executable must be small and does not
have any external dependencies.
Volunteer must have extensive experience with 3D toolkits and have done
something like this before. The task does not require any
videoconferencing experience, the videoconferencing module is supplied for
you. The volunteer must interface his/her system with the supplied
videoconferencing software via a shared memory buffer interface.
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2008-03-03 09:37:38
Admin
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| Announcements Have Been Sparse |
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2007-12-22 00:22:49
Kevin Perrott
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| Dinner with Ray Kurzweil and Aubrey de Grey!!! |
Greetings, fellow Mprize supporters!
We are very happy to invite you to what promises to be an amazing evening of food, fun, and conversation with some of the greatest thinkers in the field of healthy life extension.
On December 8, 2005, in the Boston area, the Methuselah Foundation will be hosting a small dinner party. The guests of honor will be Ray Kurzweil and our very own Aubrey de Grey! The event is free of charge.
Here's the catch: you have to be a Three Hundred member to attend. |
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2005-09-26 08:02:35
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| Science Finding Ways to Regrow Fingers |
Science Finding Ways to Regrow Fingers
Feb 18 11:33 PM US/Eastern
By MALCOLM RITTER
AP Science Writer
NEW YORK (AP) -- Researchers are trying to find ways to regrow fingers
_ and someday, even limbs _ with tricks that sound like magic spells
from a Harry Potter novel.
There's the guy who sliced off a fingertip but grew it back, after he
treated the wound with an extract of pig bladder. And the scientists
who grow extra arms on salamanders. And the laboratory mice with the
eerie ability to heal themselves.
This summer, scientists are planning to see whether the powdered pig
extract can help injured soldiers regrow parts of their fingers. And a
large federally funded project is trying to unlock the secrets of how
some animals regrow body parts so well, with hopes of applying the the
lessons to humans.
Justification - Summary - With statements like this, "But "we are very
uninformed about how all of this works," Badylak said. "There's a lot
more that we don't know than we do know.", being a glass half full type
of person I cannot help having great enthusiasm for the power of our
future regenerative medicine. In other words, with results this
promising from only knowing so little the possibilities must be
profound!
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2007-02-25 00:00:00
James Swayze
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| Andara™ Oscillating Field Stimulator (OFS) Device [Aids Nerve Regeneration - Spinal Injured Helped] |
Andara™ Oscillating Field Stimulator (OFS) Device [Aids Nerve Regeneration - Spinal Injured Helped]
The Andara™ Oscillating Field Stimulator (Andara™ OFS Device) is currently the subject of a Phase Ib clinical trial being conducted under an Investigational Device Exemption (IDE) from the FDA. The Andara OFS Device is designed to stimulate regrowth of the neural fibers surrounding the spinal cord across the area of injury to establish new neural connections that can restore function, including tactile sensation, sexual function and movement. The Andara OFS Device is designed to be used at the time of orthopedic stabilization of the injury, within 18 days of spinal cord injury. The device is removed after 14 weeks, however, improvement in function can continue for up to one year.
Published results from a ten-participant, Phase Ia trial completed in 2004 demonstrated that all participants showed statistically significant improvement in sensation and some improvement in movement, including hand, arm and leg movement.
Justification - Summary - I include this one although it might not directly be or appear capable of extending life beyond present, so called, "normal" limits as it's current use is intended. However, perhaps there is a use for it that the designers had not thought of or are for now, as far as I know, not interested in pursuing. I reason that the nerve growth this device is capable of stimulating might in a different environment and with some tweaking be able to be used to help rejuvenate neurons in the brain that have withered with age. I know I am in total speculation mode here. At least it is good news for those with spinal, and possibly other such as peripheral, nerve damage like, well, myself.
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2007-01-10 00:00:00
James Swayze
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| Rapid cooling technology could aid surgery patients, heart attack victims |
Rapid cooling technology could aid surgery patients, heart attack victims
ARGONNE, Ill. (Oct. 28, 2005) — A promising new approach to saving stroke and cardiac arrest victims is also being investigated as a technique to improve laparoscopic surgery. Researchers at Argonne National Laboratory and the University of Chicago have developed a specially engineered ice slurry that cools organs, allowing doctors more time to treat patients.
Justification - Summary - This one may be a stretch but please bare with me. Suspended Animation, sometimes called Cryonics, is actually a developing technological science with soon to be real-time benefits for, so called, mainstream medicine. Researchers working in the area of vitrification, a method of extreme cold storage for macrobiotic biological tissues, have successfully stored test kidney tissues at liquid nitrogen temperatures and revived them to room temperature utility where they proved to be viable. Routine storage of human transplant organs is figured for availability within five years. Tissue on the microscopic scale like sperm and eggs have been extreme cold (cryogenic) stored for years but whole systems of cells have been a more difficult challenge. This new technology will greatly improve the organ donation system as now it is incumbent on those performing the procedures to do so extremely quickly as the organs must be used very soon after extraction before they spoil.
Another facet to this is the discovered fact that cold temperatures protect the brain and heart from ischemia damage such that sets in after breathing is halted for too long. [See these RE News articles, 1 & 2] Hypothermia has therefore been utilized in keeping heart lung bypass surgery patients unconscious safely for up to two hours of bloodless surgery, whereupon their blood has been completely removed from their bodies. Increasingly similar cold temperature application is being used to help extend the "Golden Hour" for safer treatment of trauma victims. Such low temperatures slow down the body's degradation allowing more heroic efforts of repair and so forth to be used and prove more often successful. This procedure abve is yet another such application. Those of us in the Life Extension movement look to a time when like an astronaut on a long mission, placed in suspension to travel distance and time as well, some patients will be suspended until a more opportune moment occurs for their repair or cure, perhaps waiting for developing technology and cures to become available. I believe more and more uses such as this for cold temperature application on medical patients is yet another brick in building such a future.
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2007-01-09 00:00:00
James Swayze
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Mprize Fund
$4,743,913
SENS Fund
$7,104,132
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